Nice equipment you've got there! Congratulations.
What car do you have?
HU?? Which is this? Is it the CD changer CDX P5000 or the mini disc player?? I couldn't find more details on this HU. (I am bad on google too). Please give some more details on this.
You have a 15" ES380 sub which can do quiet a bit of loud bass. It goes very low too.
And I am seeing that you're turning on S-Bass settings on your HU. That is a crazy thing to do. Never ever go that way. Pioneer has some inbuilt EQ presets which include S-Bass, Flat and natural. It is better to keep the EQ at flat and do the tuning @ amp level. If you feel anything missing still, then you can play around with the HU eq settings but never ever turn on hi loud nor S-bass. I am speaking from my sour experience.

I would recommend to turn on the EQ-EX (if available) on your HU. It will give you some additional bass and treble controls and you can increase /decrease a certain bass frequenzy without bothering the whole setup.
Better still, call up Gunbir from Driven's place and he will help you out more better.
Before that, don't go the S-bass way!
@LBM. Day by day, I am forced to think so! LOL.