[Zen2001]

All this dubious, shady talk/rumor of vaccine-related side effects only reflects the quality of research that has gone into their manufacturing. The bottom-line is winning the race by cutting corners, bending regulations and just about keeping it legal. After all what sums it up better than this? Can it get any more crazy?

[download2live]

My understanding was that the virus was designed to make sure that the herd immunity does not develop in order to maximize damage. As Sweden realized much to their disappointment.

I think vaccine will be like a flu shot. It won't prevent flu but will make sure that if infected the intensity will be less.

[Thad E Ginathom]

"Should not be used by..." probably translates into "Has not been tested on..."

I guess it would actually be wrong for them to say to say, "Look, it's probably fine but..." Even if.

[pandey.jai]

Originally Posted by download2live

My understanding was that the virus was designed to make sure that the herd immunity does not develop..

I think vaccine will be like a flu shot. It won't prevent flu but will make sure that if infected the intensity will be less.

I don’t think it was designed in a lab. I somehow don’t.

However, the anti-vaccine is probably designed to be like a flu shot, so that people keep coming back for it. Pharma companies have to make money too.

[V.Narayan]

Originally Posted by civic-sense

Says a lot about our indigenous vaccine right? People, be careful about which vaccine you get.

Not sure where you are coming from. Or is it the usual India bashing past time. You are aware, I'm sure, about the Pfizer vaccine deaths in Norway aren't you? - link below. So let's stay with facts and keep our prejudices away from this thread as several read this thread for serious information.

All,

All the vaccines, American, British, Indian Chinese, have gone through phase I, phase II and very limited phase III trials in the interest of time. All carry some risk and for none of them do we fully know all the risks.

Clinical development is a three-phase process. During Phase I, small groups of people receive the trial vaccine. In Phase II, the clinical study is expanded and vaccine is given to people who have characteristics (such as age, gender and physical health) similar to those for whom the new vaccine is intended. In Phase III, the vaccine is given to thousands of people and tested for long term efficacy and side effects. Phase III can take a few years. Many vaccines undergo Phase IV formal, ongoing studies after the vaccine is approved and licensed.

I'm a healthcare worker {though not a doctor} and I'll be getting the shots soon. I intend to take it and get on with it. No hand wringing and endless debates on social media for me. Right through this period since late-March I've been attending to my work at hospitals. No point living in perpetual fear. At the same time don't think of this as a common viral. I have witnessed three swift deaths in my immediate circle (ages - ~45, 62, 73, 84). Take the precautions we all now know and most likely you will be fine.

https://indianexpress.com/article/ex...orway-7150517/

[civic-sense]

Originally Posted by V.Narayan

Not sure where you are coming from. Or is it the usual India bashing past time. You are aware, I'm sure, about the Pfizer vaccine deaths in Norway aren't you? - link below. So let's stay with facts and keep our prejudices away from this thread as several read this thread for serious information.

I'd rather choose my vaccine - if I can - based on data available, and not on nationalism.

Between Covishield and Covaxin I tend to feel safe going for the former than the latter. If you feel safe with the latter, then you should definitely get it. Likewise, I think all of us here has the wisdom to choose what is best for them.

Peace.

[sunilch]

Originally Posted by civic-sense

I'd rather choose my vaccine - if I can - based on data available, and not on nationalism.

Between Covishield and Covaxin I tend to feel safe going for the former than the latter. If you feel safe with the latter, then you should definitely get it. Likewise, I think all of us here has the wisdom to choose what is best for them.

Peace.

I feel most of us are making conclusion or sharing our opinion against Covaxin based on what we have read so far in the Media.

I would personally want to know more about it via someone who may have a better understanding or access to data. For example, I would prefer to rely on the opinion of a doctor when the vaccine becomes available to general public for purchase.

Until that point trying to decide which vaccine to take or not take is pointless.

Covishield and Covaxin - both are nearly in same boat at present and are being given to essential workers by the government. Nothing can be done here by us or for us.

Since we have managed to live with this Wuhan Virus for over a year now, I guess we should be able to live with it for another six months easily (unless we discover a newer deadlier virus and we again star scrambling for solutions) by when we will have better data available.

[srishiva]

I feel for the makers of Covaxin. All their work in developing it is being painted with malice. I think the govt has also played a part in it. They could have stockpiled it and waited for the complete trials and results and then released it.

The current govt does things in a way that annoys people even if it has to be done and there is nothing wrong in intent

For Covishield are we following the half dosage followed by full one or are we supposed to follow the trial process that was done in our country ?

[am1m]

Originally Posted by Thad E Ginathom

I guess it would actually be wrong for them to say to say, "Look, it's probably fine but..." Even if.

Actually that's sorta what the literature says, in this case for the IPV (polio vaccine):

"Although there is no evidence that polio vaccine virus causes harm to pregnant women or their fetuses, pregnant women not at increased risk should not receive the polio vaccine."

https://www.cdc.gov/vaccines/vpd/pol...ecautions.html

Also, for some time, there were even doubts about the efficacy of the IPV vaccine. https://www.who.int/ihr/polio1993en.pdf

And that's for a vaccine that's been around for decades and has proven beyond all doubt to be extremely key in eradicating polio.

So it should be of little surprise that these same kinds of issues are coming up for any brand new vaccine for a new virus.

The point is all these things we're seeing have been seen in past epidemics too and the course an epidemic will take and a vaccine will go through will be more or less the same. The difference is the immediacy and the relevance with which the media are blowing up each of these instances and incidents. So it is more important than ever to choose our sources of information wisely. Whatsapp uni is the worst, but most of the mainstream media are not much better. Unless you can read through the various medical papers and understand the limits and conclusions of the studies they document, we're probably better off talking to doctors we trust to explain what each new development means before either panicking or choosing to ignore it.

[srini1785]

Originally Posted by srishiva

I feel for the makers of Covaxin. All their work in developing it is being painted with malice. I think the govt has also played a part in it. They could have stockpiled it and waited for the complete trials and results and then released it.

The current govt does things in a way that annoys people even if it has to be done and there is nothing wrong in intent

So the GOI does this to build confidence :

https://www.ndtv.com/india-news/pm-m...ndtv_topscroll

[comfortablynumb]

Originally Posted by srishiva

For Covishield are we following the half dosage followed by full one or are we supposed to follow the trial process that was done in our country ?

At least according to this report, the DGCI approval has been given based on the 2 full dose method, and that's what they will be following in practise.

[DigitalOne]

Originally Posted by DigitalOne

Here is the official recommendation from the ministry of health website

Please note recommendations are the same for both the vaccines.

Originally Posted by DigitalOne

Both vaccines are giving very similar recommendations. Covishield is shirking responsibility and leaving the decision to the health care provider and the receiver, so they are absolved of any adverse effects.

Source: Covishield Factsheet ;Covaxin Factsheet

Originally Posted by civic-sense

I'd rather choose my vaccine - if I can - based on data available, and not on nationalism.

The safety recommendation on who should (or should not) take the vaccine, is the same for both Covishield and Covaxin.

I have linked the company factsheets and the official government recommendation.

For any of the 'high risk' receivers like pregnant women or lactating women, the only difference is in the terminology used.
Covishield: "Please check with your healthcare provider....."
Covaxin: "It is advised not to....."

Before going with a decision, it is better to check official recommendations rather than media reports (which are written by junior reporters with no medical background).

[Gansan]

There is always going to be certain unknown factors about all of the new vaccines, from whatever country. That will be known only when they are studied for at least five years. But the world does not have that kind of time. The problem is here and now.

Anyway vaccination is not compulsory in India. If anyone has misgivings, instead of ridiculing the vaccines, just don't register your names and don't get vaccinated. It is up to you. Simple.

[carboy]

Originally Posted by Gansan

Anyway vaccination is not compulsory in India. If anyone has misgivings, instead of ridiculing the vaccines, just don't register your names and don't get vaccinated. It is up to you. Simple.

What if I have misgivings about one vaccine but not about the other. What should I do?

[Gansan]

Originally Posted by carboy

What if I have misgivings about one vaccine but not about the other. What should I do?

Wait for a few months. The Government will allow leading hospitals to procure and administer vaccines on payment basis, sooner than later. We will be able to choose vaccine A over Vaccine B or C or D or even more. That is what I plan to do for my entire family.

We need not be apprehensive about Covaxin. By the time vaccination starts for the general public, the third stage trial data will be out and we may probably find it more attractive than Covishield. Who knows.

It uses inactivated virus, which I understand is one of the most tried and tested mediums for various vaccines the world uses for various diseases.