[Thad E Ginathom]

Finding some good things in the international news today

Oxford coronavirus vaccine triggers immune response, trial shows.

Trial of Covid-19 drug given via inhaler 'very promising', say scientists

Both from UK's The Guardian. Thad-Approved newspaper

[proton]

Originally Posted by joslicx

Its not like all virologists, microbiologists, epidemiologists and immunologists have the exact same opinion! in fact there can be multitude of opinions and I think mostly the govt has been doing what a majority of them have been advocating...

Regarding just one point, did any epidemiologist recommend anything other than test, trace, and isolate, when the figure was 1000-2000 cases for entire India, ie when it was easily manageable? When the government said Indians have a different immune response due to BCG, race, etc, in rejecting all the advice?

[am1m]

Originally Posted by akshaymahajan

Does anyone here have details on how to go about getting a Covid test in Bangalore?

(Had posted earlier)

"...a friend in Bangalore has opted to get tested because a family member started showing symptoms last week. They were able to call SRL diagnostics who said they would come to the house and collect samples."

Update on that case: the test for the patient and the family members came out negative, but before the test results came out, the family insisted on moving the patient to the hospital because he had several underlying conditions like hypertension and diabetes. So he remained in the hospital (one of the bigger private hospitals in Bangalore, that he said was very understaffed) for a couple of days, was given oxygen a couple of times (not a ventilator) and now he's back home doing fine. He says he was more worried about getting the virus in the hospital while waiting for hours in the general areas with several potential cases.

[itwasntme]

Dependable news given the accuracy of these tests?

https://twitter.com/velumania/status...066390528?s=09

This study is based on data from 60,000 antibody tests conducted across 600 pin codes over 20 odd days. Their estimate is that nearly 15% may already have antibodies against the novel coronavirus.

[PearlJam]

Originally Posted by itwasntme

Dependable news given the accuracy of these tests?

https://twitter.com/velumania/status...066390528?s=09

Logically makes sense to me, and fits in with my thought process. But, this is not a verified twitter handle, and looks a bit crude, if I may say so. Hopefully more verified information will come out in the coming weeks.

[DigitalOne]

Originally Posted by Thad E Ginathom

Finding some good things in the international news today

Oxford coronavirus vaccine triggers immune response, trial shows.

The best thing about this Oxford-AstraZeneca vaccine? There is already partnership with Serum institute of India (World's largest manufacturer of vaccines) to mass manufacture this vaccine. They are planning to manufacture the vaccine in parallel to the phase 3 trials, so it is ready to be delivered quickly.

source

This is why I keep telling repeatedly, this virus doesn't stand a chance against Human ingenuity .

[srishiva]

Originally Posted by Thad E Ginathom

Finding some good things in the international news today

Oxford coronavirus vaccine triggers immune response, trial shows.

Trial of Covid-19 drug given via inhaler 'very promising', say scientists

Both from UK's The Guardian. Thad-Approved newspaper

Feel for the 3 patients who died getting placebo :(

I think they will start the phase 3 trials of the vaccine in India too. They might get good candidates in hot spot areas of the country and can cover people who have co-morbidness.

[harry10]

Received this on whatsapp yesterday. Most people around me are doing this mistake. There is no point correcting them as they simply don't understand this concept.

[archat68]

Originally Posted by srishiva

Feel for the 3 patients who died getting placebo :(

Patients do not get the vaccines. Vaccines are for healthy subjects only.

Only tested negative, asymptomatic subjects (NOT patients) get vaccines. Anyway in any trial one group gets the trial drug and other group gets placebo or the comparator drug. In any case the placebo group is always given standard of care whatever is available at that point as treatment. In a drug trial you have to prove that the study is atleast non-inferior or superior to the comparartor drug which is usually a gold standard drug at that point of time. In vaccine trial you have to show that you generate enough protective antibody and that antibody stays how much in your body (need for booster dose).

[srishiva]

Originally Posted by archat68

Patients do not get the vaccines. Vaccines are for healthy subjects only.

Only tested negative, asymptomatic subjects (NOT patients) get vaccines....

The comment was for the inhaler medicine

[ninjatalli]

Originally Posted by Thad E Ginathom

Both from UK's The Guardian. Thad-Approved newspaper

Mine too!

And all news involving the researchers involved in the above are very guarded and not widely promising anything (like the surety of the vaccine being ready by a certain date). Much more confidence inspiring than the previous supposedly successful claims by other(s) in the last few weeks. Keeping fingers crossed.

[Thad E Ginathom]

Originally Posted by DigitalOne

The best thing about this Oxford-AstraZeneca vaccine? There is already partnership with Serum institute of India (World's largest manufacturer of vaccines) to mass manufacture this vaccine. They are planning to manufacture the vaccine in parallel to the phase 3 trials, so it is ready to be delivered quickly.

This is very good news indeed. And was able to read both items in my Indian newspapers today too.

The Guardian makes good points about distribution. Sadly, there is so much more to human nature than ingenuity, and both political egos and corporate greed are likely to play a part. I wonder if Indian vaccine will be delivered to Indian people? Affordably? Let us hope so.

[DigitalOne]

Originally Posted by DigitalOne

For the last few days, the founder-chairman of Thyrocare has been tweeting actual data analysis from antibody tests done at Thyrocare centres. He has also posted pin code wise data of the antibody +ve results. Some of the areas (in Thane) are showing 47% positive results. Per him, 15% of Indians have been infected, that is, 18 crore cases!!.

Do please go through his twitter timeline to read some pretty interesting data and make your own assessments.

Originally Posted by itwasntme

Dependable news given the accuracy of these tests?

https://twitter.com/velumania/status...066390528?s=09

This study is based on data from 60,000 antibody tests conducted across 600 pin codes over 20 odd days. Their estimate is that nearly 15% may already have antibodies against the novel coronavirus.

Originally Posted by PearlJam

Logically makes sense to me, and fits in with my thought process. But, this is not a verified twitter handle, and looks a bit crude, if I may say so. Hopefully more verified information will come out in the coming weeks.

I had quoted the same twitter thread yesterday. Though it is not a verified twitter (blue tick) account, this is verified to be Thyrocare's founder-Chairman's account.

---
Govt has released official data of the Sero Survey conducted in Delhi between June 27th to July 10th.

Delhi sero-survey reported that on an average, across Delhi, the prevalence of IgG antibodies is 23.48 per cent. The study conducted by the National Center for Disease Control (NCDC)also indicates that a large number of infected persons remain asymptomatic. The survey was conducted from 27 June 2020, to 10 July 2020.

A total of 21,387 samples were collected as per lab standards and were tested. The tests done help in identification of the presence of antibodies in the general population.

Source

[msdivy]

Originally Posted by balenoed_

Some sensible decision here:

The reason lockdown is lifted is Govt needs money. It is estimated KA needs 6,500 Cr per month for running the state machinery. With no economic activity, reduced tax the Govt can't maintain same lifestyle

Bengaluru: Lockdown no solution, restrictions only in containment zones, says CM Yediyurappa - Better than late than never realization. According to the article, experts have suggested 5T strategy - Trace, Track, Test, Treat and Technology, which will be followed.

"There'll be no lockdown from tomorrow, people need to get back to work, economy is also very important. Lockdown is not the solution, now restrictions will be placed only in containment zones," CM said today.

Any questions on saving the population in lieu of the economy?

Lockdown was meant to ramp up medical supplies. Govt setup wedding halls, designated hotels, railway carriages for quarantine & treatment. But why still there is shortage os PPEs, beds? Many doctors have closed down their clinics due to lack of PPE for safe practice. This is affecting non-covid patients.

Lockdown is the ultimate Brahmastra weapon, which was used in 1st round and got wasted. Now when the real battle is begun, that weapon can't be used again.

[akshaymahajan]

Originally Posted by am1m

(Had posted earlier)

"...a friend in Bangalore has opted to get tested because a family member started showing symptoms last week. They were able to call SRL diagnostics who said they would come to the house and collect samples."

Thanks a tonne. Called them yesterday morning and they collected the sample today. Took under 10 minutes with most of the time being spent by the tech in getting into and getting out of the PPF gear

All they need is a Govt ID.

Cost: 4500